Type 2 diabetes (T2D) is heterogeneous and associated with a diverse range of risk factors from individuals’ biological and clinical characteristics to environmental exposures and social determinants of health (SDoH).
Alzheimer’s Disease (AD), accounting for 80% of dementia cases, is a neurodegenerative disease characterized by progressive loss of memory and cognition, among other neurobehavioral symptoms.
Published in Science of the Total Environment, 2021
The incidence of childhood atopic dermatitis (AD) and allergic rhinitis (AR) is increasing. This warrants development of measures to predict and prevent these conditions. We aimed to investigate the predictive ability of a spectrum of data mining methods to predict childhood AD and AR using longitudinal birth cohort data. We conducted a 14-year follow-up of infants born to pregnant women who had undergone maternal examinations at nine selected maternity hospitals across Taiwan during 2000–2005.
Published in IEEE Transactions on Knowledge and Data Engineering, 2022
Arrhythmia detection from ECG is an important research subject in the prevention and diagnosis of cardiovascular diseases. The prevailing studies formulate arrhythmia detection from ECG as a time series classification problem. Meanwhile, early detection of arrhythmia presents a real-world demand for early prevention and diagnosis. In this paper, we address a problem of cardiovascular diseases early classification, which is a varied-length and long-length time series early classification problem as well.
Published in Knowledge-based Systems, 2022
Predicting the air quality index (AQI) has been regarded as a critical problem for environmental control management. Many factors over time and space may relate to the diffusion of pollutants. In other words, there exist very intricate spatio-temporal interactions among the characteristic for revealing diffusion of pollutants. Recently, some relevant works studied the topic of AQI prediction considering spatial and temporal correlations simultaneously, but most of them either ignore geospatially topological structures to learn spatio-temporal dependency or utilize sub-modules separately to encode the spatial and temporal information. Unfortunately, ignoring geospatially topological structures or correlations among spatial properties and temporal dependencies leads that the AQI prediction model cannot deal with the prediction task well…
Published in IEEE Transactions on Neural Networks and Learning Systems, 2022
Early time series classification predicts the class label of a given time series before it is completely observed. In time-critical applications, such as arrhythmia monitoring in ICU, early treatment contributes to the patient’s fast recovery, and early warning could even save lives. Hence, in these cases, it is worthy of trading, to some extent, classification accuracy in favor of earlier decisions when the time series data are collected over time. In this article, we propose a novel deep reinforcement learning-based framework, snippet policy network V2 (SPN-V2), for long and varied-length multi-lead electrocardiogram (ECG) early classification.
Published in IEEE Journal of Biomedical and Health Informatics, 2022
Cardiovascular diseases (CVDs) are considered the greatest threat to human life according to World Health Organization. Early classification of CVDs and the appropriate follow-up treatment are crucial for preventing sudden deaths. Electrocardiogram (ECG) is one of the most common non-invasive tools used to evaluate the state of the heart, which can be exploited to automatically diagnose as well. However, the importance of diagnosing CVDs is varying in different context-specific scenarios….
Published in American Diabetes Association, 2024
T2D is a heterogeneous disease with variations in presentation, progression, and response to treatments across individuals. We developed a novel GNN-based framework to identify distinct T2D progression pathways using electronic health records (EHR) data.
Published in Journal of Biomedical Informatics, 2024
The integration of artificial intelligence (AI) and machine learning (ML) in health care to aid clinical decisions is widespread. However, as AI and ML take important roles in health care, there are concerns about AI and ML associated fairness and bias. That is, an AI tool may have a disparate impact, with its benefits and drawbacks unevenly distributed across societal strata and subpopulations, potentially exacerbating existing health inequities. Thus, the objectives of this scoping review were to summarize existing literature and identify gaps in the topic of tackling algorithmic bias and optimizing fairness in AI/ML models using real-world data (RWD) in health care domains.
Published in Nature Communications, 2024
Racial and ethnic minorities bear a disproportionate burden of type 2 diabetes (T2D) and its complications, with social determinants of health (SDoH) recognized as key drivers of these disparities. Implementing efficient and effective social needs management strategies is crucial…
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This is a presentation of the study “Care coordination and patient safety outcome: a graph-based approach”
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This is a presentation of the study “Developing A Fair Individualized Polysocial Risk Score (iPsRS) for Identifying Increased Social Risk of Hospitalizations in Patients with Type 2 Diabetes (T2D)”
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This is a course about foundation of machine learning methods.
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This is a talk about how to create health digital twin using real-world data.
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Real World Data (RWD), including electronic health records (EHR), claims, and billing data, capture detailed, longitudinal patient information, covering demographics, comorbidities, treatments, and outcomes. They have become as a vital data source reflecting real-world patient populations and clinical settings. Applying AI/ML models to RWD have generated insights and real-world evidence (RWE), such as predicting disease onset risk, modeling progression pathways, and supporting more nuanced patient stratification strategies. AI-derived RWE increasingly informs clinical and regulatory decisions.
Undergraduate course, University 1, Department, 2014
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Workshop, University 1, Department, 2015
This is a description of a teaching experience. You can use markdown like any other post.